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Antigenic Specificity | RASA1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of RASA1 protein. RAS P21 Protein Activator 1 encoded by RASA1 is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous ma |
Immunogen | Immunogen: Synthesized peptide derived from part region of human RASA1 protein |
Other Names | [Rabbit RASA1; Ras GTPase-activating protein 1; GAP; GTPase-activating protein; RasGAP; Ras p21 protein activator; p120GAP] |
Gene, Accession # | [RASA1], Gene ID: 5921, NCBI: P20936.1, UniProt: P20936 |
Catalog # | MBS9710638 |
Price | $130, $220, $325 |
Order / More Info | RASA1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |