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Antigenic Specificity | Human CD206 |
Clone | [15.2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | fluorescein (FITC) conjugate |
Size | 20 tests, 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Macrophage mannose receptor (MMR) is a 162-175 kD type I membrane protein also known as CD206, MRC1, or mannose receptor (MR). It is a pattern recognition receptor (PRR) that belongs to C-type lectin superfamily. MMR is expressed on macrophages, dendritic cells, and hepatic or lymphatic endothelial cells, but not on monocytes. MMR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine. MMR mediates endocytosis and phagocytosis, induces activation of macrophages and antigen presentation, plays an important role in host defense, and provides a link between innate and adaptive immunity. |
Immunogen | n/a |
Other Names | [CLEC13D; CLEC13DL; MRC1L1; MMR; hMR] |
Gene, Accession # | [CD206], Gene ID: 4360, NCBI: NP_002429.1, UniProt: P22897 |
Catalog # | MBS2559156 |
Price | $100, $125, $165 |
Order / More Info | Human CD206 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |