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Antigenic Specificity | Human CD11a |
Clone | [4ATS1; 22.1.1.13] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 100 tests, 500 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | 4ATS1/22.1.1.13 reacts with CD11a, a 180 kDa molecule. CD11a is the a chain of the leukocyte function associated antigen-1 (LFA-1a), and is expressed on all leukocytes including T and B cells, monocytes, and granulocytes, but is absent on non-hematopoietic tissue and human platelets. CD11/CD18 (LFA-1), a member of the integrin subfamily, is a leukocyte adhesion receptor that is essential for cell-to-cell contact, such as lymphocyte adhesion, NK and T-cell cytolysis, and T-cell proliferation. CD11/CD18 is also involved in the interaction of leucocytes with endothelium.*CD11a antibody has been used to reduces graft failure for bone marrow grafts in immunodeficient children. This clone is cross reactive with non-human primate. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | [CD11a] |
Catalog # | MBS8501226 |
Price | $280, $350 |
Order / More Info | Human CD11a Antibody from MYBIOSOURCE INC. |
Product Specific References | 1.Schlossman. S et al. (1995) Leucocyte Typing V: White Cell Differentiation Antigens. Oxford University Press. New York. 2.Lub M et al. (1995) Immunol. Today 16:479. 3.Sanchez-Mateos P et al. (1996) Cancer Biol. 7:99. |