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Antigenic Specificity | IRAK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-IRAK2 [Rabbit antibody to peptide corresponding to aa 546-564 of human IRAK2.]. This antibody recognizes full-length human IRAK2 (65 kD). The pro-inflammatory cytokine IL-1 induces cellular responses through two subunits of its receptor, IL-1 receptor 1 (IL-1R1) and IL- 1 receptor accessory protein (IL-1RacP). IL-1 receptor-associated kinase (IRAK) mediates activation of NF- kappa B, a key transcription factor that mediates inflammatory and immune respones. A novel member of the IRAK/Pelle family was recently identified and designated IRAK2. Both IRAK and IRAK2 associate with the subunits of the IL-1R complex after IL-1 binding and lead to NF- kappa B activation. IRAKs also associate with Toll-like receptor (TLR) and the d |
Immunogen | Antigen: Peptide corresponding to aa 546- 564 of human IRAK2. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS194111 |
Price | $415 |
Order / More Info | IRAK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |