LTA Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | LTA |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: LTA antibody detects endogenous levels of total LTA. Description: Lymphotoxin-alpha (LT-alpha), also known as TNF-beta, is a member of the TNF superfamily of proteins (1). NK cells, T cells, B cells, and lymphoid tissue-inducer cells express LT-alpha (1). LT-alpha can be secreted as a soluble homotrimer or form membrane bound heterotrimers with lymphotoxin-beta (LT alpha1beta2 or LT alpha2beta1) which can be cleaved from the cell surface by matrix metalloproteases (1, 2). Soluble LT-alpha binds to and signals through TNFR1/TNFR2, activating the canonical NF-kappaB pathway (1). In contrast, LT alpha1beta2 heterodimers bind to the LTbetaR receptor and activate the noncanonical NF-kappaB pathway (1). As a result, LT-alpha and TNF- |
| Immunogen | Immunogen: A synthesized peptide derived from human LTA Subcellular Location: Secreted. Membrane. The homotrimer is secreted. The heterotrimer is membrane-associated. Predicted Cross Reactivity: Horse, Dog Similarity: Horse (89%), Dog (89%) |
| Other Names | [LTalpha; DIF; LT alpha; LT; LT-alpha; Lta; Lymphotoxin alpha (TNF superfamily, member 1); Lymphotoxin alpha; Lymphotoxin-alpha; TNF B; TNF superfamily member 1; TNF, lymphocyte-derived; TNF-beta; TNFB; TNFB_HUMAN; TNFbeta; TNFSF1; TNLG1E; Tumor necrosis factor beta; tumor necrosis factor ligand 1E; Tumor necrosis factor ligand superfamily member 1] |
| Gene, Accession # | [LTA], Gene ID: 4049, NCBI: NP_000586.2, UniProt: P01374 |
| Catalog # | MBS9607110 |
| Price | $240, $280 |
| Order / More Info | LTA Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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