PAXIP1 (N-term) Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | PAXIP1 (N-term) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PAXIP1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2-35 amino acids from the N-terminal region of human PAXIP1. Involved in DNA damage response and in transcriptional regulation through histone methyltransferase (HMT) complexes. Plays a role in early development. In DNA damage response is required for cell survival after ionizing radiation. In vitro shown to be involved in the homologous recombination mechanism for the repair of double-strand breaks (DSBs). Its localization to DNA damage foci requires RNF8 and UBE2N. Recruits TP53BP1 to DNA damage foci and, at least in particular repair processes, effective DNA damage response appears to require the association with TP53BP1 phosphorylat |
| Immunogen | n/a |
| Other Names | [PAX-interacting protein 1; PAX transactivation activation domain-interacting protein; PAXIP1; PAXIP1L; PTIP] |
| Gene, Accession # | [PAXIP1], Gene ID: 22976, NCBI: NP_031375.3, UniProt: Q6ZW49 |
| Catalog # | MBS9209909 |
| Price | $165, $370 |
| Order / More Info | PAXIP1 (N-term) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Ota T.,et al.Nat. Genet. 36:40-45(2004). Bechtel S.,et al.BMC Genomics 8:399-399(2007). Hillier L.W.,et al.Nature 424:157-164(2003). Margolis R.L.,et al.Hum. Genet. 100:114-122(1997). Manke I.A.,et al.Science 302:636-639(2003). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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