DOCK7 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | DOCK7 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: DOCK7 antibody detects endogenous levels of total DOCK7. Function: Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation; negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).Subunit S |
| Immunogen | Immunogen: A synthesized peptide derived from human DOCK7 Subcellular Location: Cell Projection, Axon. Note=Enriched in the developing axons of hippocampal neurons. Tissue Specificity: Widely expressed. Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (100%), Sheep (91%), Rabbit (100%), Dog (100%) |
| Other Names | [3110056M06Rik; dedicator of cytokinesis 7; Dedicator of cytokinesis protein 7; Gm430; KIAA1771; MGC189434; mKIAA1771; RP23 329P19.2; ZIR2] |
| Gene, Accession # | [DOCK7], Gene ID: 85440, NCBI: NP_001258928.1, UniProt: Q96N67 |
| Catalog # | MBS9609750 |
| Price | $240, $280 |
| Order / More Info | DOCK7 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.