HUS1 - middle region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHUS1 - middle region
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThe protein encoded by this gene is a component of an evolutionarily conserved, genotoxin-activated checkpoint complex that is involved in the cell cycle arrest in response to DNA damage. This protein forms a heterotrimeric complex with checkpoint proteins RAD9 and RAD1. In response to DNA damage, the trimeric complex interacts with another protein complex consisting of checkpoint protein RAD17 and four small subunits of the replication factor C (RFC), which loads the combined complex onto the chromatin. The DNA damage induced chromatin binding has been shown to depend on the activation of the checkpoint kinase ATM, and is thought to be an early checkpoint signaling event. Alternative splicing results in multiple transcript variants.
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the middle region of human HUS1
Other Names[checkpoint protein HUS1 isoform 1; Checkpoint protein HUS1; checkpoint protein HUS1; HUS1 checkpoint clamp component]
Gene, Accession #[HUS1], Gene ID: 3364, NCBI: NP_004498.1, UniProt: O60921
Catalog #MBS3223235
Price$335
Order / More InfoHUS1 - middle region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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