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Antigenic Specificity | PODXL2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PODXL2 antibody detects endogenous levels of total PODXL2. Function: Acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P-and L-selectins.Subunit Structure: Homodimer; disulfide-linked. Interacts with SELL, SELE and SELP.Post-translational Modifications: Glycosylated; contains chondroitin sulfate. Displays sialylated O-linked oligosaccharides. Sulfation is necessary for interaction with SELL. Sialylated O-linked oligosaccharides are necessary for interaction with SELL, SELE and SELP.Similarity: Belongs to the podocalyxin family. |
Immunogen | Immunogen: A synthesized peptide derived from human PODXL2 Subcellular Location: Membrane; Single-Pass Type I Membrane Protein Tissue Specificity: Expressed in T-cells, B-cells and monocytes. Expression is higher on memory and germinal center cells than on naive B-cells (at protein level). Highly expressed in brain. Moderately expressed in pancreas, kidney and lymphoid node. Weakly expressed in liver. Detected in both endothelial cells and CD34 bone marrow cells. Predicted Cross Reactivity: Pig, |
Other Names | [EG; OTTHUMP00000216064; PODLX2; podocalyxin like 2; Podocalyxin like protein 2; PODXL2] |
Gene, Accession # | [PODXL2], Gene ID: 50512, NCBI: NP_056535.1, UniProt: Q9NZ53 |
Catalog # | MBS9603029 |
Price | $240, $280 |
Order / More Info | PODXL2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |