ELAVL1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityELAVL1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatperoxidase (HRP) conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionRNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability. Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), stabilizing them, promoting ESCs differentiation. Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA, and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro. With ZNF385A, binds the 3'-UTR of p53/TP53 mRNA to control their nuclear export induced by CDKN2A. Hence, may regulate p53/
ImmunogenImmunogen: Recombinant human ELAV-like protein 1 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-5483 / sc-20694
Other Names[ELAV-like protein 1; ELAVL1; HUR; Hu-antigen R; HuR], [ELAVL1; ELAVL1; HUR; Hua; MelG; ELAV1; HUR; HuR]
Gene, Accession #[ELAVL1], Gene ID: 1994, NCBI: NP_001410.2, UniProt: Q15717
Catalog #MBS1492478
Price$160, $235
Order / More InfoELAVL1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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