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Antigenic Specificity | ELAVL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peroxidase (HRP) conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability. Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), stabilizing them, promoting ESCs differentiation. Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA, and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro. With ZNF385A, binds the 3'-UTR of p53/TP53 mRNA to control their nuclear export induced by CDKN2A. Hence, may regulate p53/ |
Immunogen | Immunogen: Recombinant human ELAV-like protein 1 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-5483 / sc-20694 |
Other Names | [ELAV-like protein 1; ELAVL1; HUR; Hu-antigen R; HuR], [ELAVL1; ELAVL1; HUR; Hua; MelG; ELAV1; HUR; HuR] |
Gene, Accession # | [ELAVL1], Gene ID: 1994, NCBI: NP_001410.2, UniProt: Q15717 |
Catalog # | MBS1492478 |
Price | $160, $235 |
Order / More Info | ELAVL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |