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Antigenic Specificity | E3 UBIQUITIN-PROTEIN Ligase CBL (pTyr700) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti E3 ubiquitin-protein ligase CBL (pTyr700) antibody recognizes the Casitas B-lineage lymphoma (CBL) E3 ubiquitin ligase, also known as c-CBL proto-oncogene and ring finger protein 55, when phosphorylated at tyrosine 700. The CBL protein is a RING finger E3-ubiquitin ligase that plays a key role in signal transduction through mediating monoubiquitination and endocytosis of receptor tyrosine kinases (Haglund et al. 2002, Dikic and Giordano 2003). E3 ubiqutin-protein ligase CBL is phosphorylated at tyrosine 700 by Fyn, Yes and Syk (Feshchenko et al. 1998). |
Immunogen | Immunogen: Phospho specific-peptide corresponding to residues surrounding tyrosine 700 of human E3 ubiqutin-protein ligase CBL |
Other Names | [E3 UBIQUITIN-PROTEIN Ligase CBL (pTyr700)], [CBL; CBL; CBL2; NSLL; C-CBL; RNF55; FRA11B; CBL2; RNF55] |
Gene, Accession # | [CBL], Gene ID: 867, NCBI: P22681.2, UniProt: P22681 |
Catalog # | MBS225224 |
Price | $375 |
Order / More Info | E3 UBIQUITIN-PROTEIN Ligase CBL (pTyr700) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |