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Antigenic Specificity | CD4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD4, a single-pass type I transmembrane glycoprotein, is found on a T cell subset (helper/inducer) representing 45% of peripheral blood lymphocytes. It is also present on 80% of thymocytes and at a lower level on monocytes. It is an accessory protein for MHC class-II antigen/T-cell receptor interaction, and may regulate T-cell activation, induce the aggregation of lipid rafts. Upon HIV-1 binding to the cell membrane, CD4 interacts with HIV-1 envelope polyprotein gp160 and protein Vpu with presence of HIV-1 gp120. |
Immunogen | n/a |
Other Names | [CD4 antigen; T-cell surface glycoprotein CD4; T-cell surface antigen T4/Leu-3], [CD4; CD4; CD4mut] |
Gene, Accession # | [CD4], Gene ID: 920, NCBI: CAA60883.1, UniProt: Q13969 |
Catalog # | MBS460219 |
Price | $285 |
Order / More Info | CD4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |