SIGLEC8 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySIGLEC8
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration2.4 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total SIGLEC8 protein. Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein.
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthetic peptide corresponding to residues near the C terminal of human sialic acid binding Ig-like lectin 8
Other Names[SAF2; SIGLEC-8; SIGLEC8L]
Gene, Accession #[SIGLEC8], Gene ID: 27181, NCBI: NP_055257.2, UniProt: Q9NYZ4
Catalog #MBS9407094
Price$255
Order / More InfoSIGLEC8 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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