PML - C-terminal region Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PML - C-terminal region |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | cow, dog, guinea pig, horse, human, mouse, porcine, rabbit, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: isoform 1, 9, 10 and 11 specific. This is a rabbit polyclonal antibody against PML. It was validated on Western Blot using a cell lysate as a positive control.Target Description: PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. PML localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this |
| Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PML |
| Other Names | [PML protein, partial; Protein PML; protein PML; promyelocytic leukemia; Promyelocytic leukemia protein; RING finger protein 71; Tripartite motif-containing protein 19] |
| Gene, Accession # | [PML], Gene ID: 5371, NCBI: AAI39796, UniProt: P29590 |
| Catalog # | MBS3201296 |
| Price | $335 |
| Order / More Info | PML - C-terminal region Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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