STAT1 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | STAT1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, rat, mouse |
| Isotype | n/a |
| Format | epitope affinity purified |
| Size | 0.1 mg |
| Concentration | Size: 100 ug/200 ul |
| Applications | ELISA, Western Blot, Immunohistochemistry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes STAT1 protein. It reacts to human, mouse and rat. The other species are not tested. STAT proteins (Signal transducer and activator of transcription) belong to a family of cytoplasmic transcription factors that can be phosphorylated by a lignad binding to its cell surface receptor. The phosphorylation of STAT1 at Tyr701 induces STAT1 dimerization, nuclear translocation and DNA binding. STAT 1 is activated by a number of different ligands, including IFN, EGF, PDGF and IL6. Tyrosine 701 phosphorylation impairment results in loss of STAT 1 functions. |
| Immunogen | Antigen Preparation: A synthetic peptide surrounding to the C-terminus of STAT1 protein from human, mouse and rat origins. |
| Other Names | [Rabbit STAT1; Signal transducer and activator of transcription 1 (STAT1)], [stat1; XStat1] |
| Gene, Accession # | [STAT1], Gene ID: 398324, NCBI: NP_001082256.1 |
| Catalog # | MBS462139 |
| Price | $275 |
| Order / More Info | STAT1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Tong R Wu, et al. SHP-2 Is a Dual-specificity Phosphatase Involved in Stat1 Dephosphorylation at Both Tyrosine and Serine Residues in Nuclei, J. Biol. Chem., Vol. 277, Issue 49, 47572-47580, December 6, 2002 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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