Human CD48 (BCM1) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CD48 (BCM1) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | Protein A purified |
| Size | 0.1 mg, 0.2 mg |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD48 is a glycosylphosphatidylinositol -anchored protein belonging to the CD2 subfamily. It is expressed mainly on hematopoietic cells and exists in both membrane- associated and soluble forms. It is a low-affinity ligand for CD2 and is implicated as an important costimulatory molecule in lymphocyte activation. Indeed, CD48 has been described as facilitating cell adhesion, innate responses to bacterial infection, and graft rejection. In addition, CD48 is a high- affinity ligand for 2B4. CD48-2B4 interactions can modulate T cell, B cell, and natural killer (NK) cell functions and cross-talk.The absence of functional 2B4- CD48 interactions impairs NK cell cytotoxic response and IFN- release on tumor target exposure. Furthermore, activated NK |
| Immunogen | Source Note: Polyclonal CD48 antibody was produced from sera of rabbits immunized with recombinant human CD48. |
| Other Names | [Rabbit Human CD48 (BCM1) purified; cd48; cd-48; cd-48; cd48; BCM1; PAb], [CD48; BCM1; BLAST1; SLAMF2] |
| Gene, Accession # | [CD48], Gene ID: 962, NCBI: NP_001769.2, UniProt: P09326 |
| Catalog # | MBS551031 |
| Price | $375, $495 |
| Order / More Info | Human CD48 (BCM1) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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