STAT3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySTAT3
Clone[4C8-1C9-H8]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat, monkey, hamster
IsotypeIgG1
Formatunconjugated
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionEntrez Summary: The protein encoded by this gene is a member of the STAT protein family.In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2.This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis.The small GTPase Rac1 has been shown to bind and regulate the activity of this protein.PIAS3 protein
ImmunogenImmunogen: Purified recombinant human STAT3 protein fragments expressed in E Coli. Sensitivity: This antibody detects endogenous levels of total STAT3 and does not cross-react with related proteins. Sequence Similarities: Belongs to the transcription factor STAT family.Contains 1 SH2 domain.
Other Names[1110034C02Rik; Acute Phase Response Factor; Acute-phase response factor; APRF; AW109958; DNA binding protein APRF; FLJ20882; HIES; MGC128731; MGC16063; MGC93551; Signal transducer and activator of transcription 3 (acute-phase response factor); Signal transducer and activator of transcription 3; STAT 3; Stat3; STAT3_HUMAN; Transcription factor], [APRF; HIES.]
Gene, Accession #[STAT3], Gene ID: 6774, NCBI: NP_003141.2, UniProt: P40763
Catalog #MBS475199
Price$335
Order / More InfoSTAT3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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