Cytokeratin 1 (Suprabasal Keratinocyte Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCytokeratin 1 (Suprabasal Keratinocyte Marker)
Clone[LHK1]
Host SpeciesMouse
Reactive Specieshuman, rat
IsotypeIgG2a, kappa
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10). Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis.
ImmunogenImmunogen: A 13-amino acid peptide (VRFVSTSYSGVTR) from the C-terminus of human KRT1 protein
Other Names[67kDa Cytokeratin; CK1; Cytokeratin-1; EHK1; Epidermolytic hyperkeratosis 1; EPPK; K1; Keratin Type II Cytoskeletal 1; Keratin-1; KRT1; KRT1A; NEPPK; Type II cytoskeletal 1; Type-II keratin Kb1]
Gene, Accession #[KRT1], Gene ID: 3848, NCBI: NP_006112.3, UniProt: P04264
Catalog #MBS4381043
Price$190, $340, $340
Order / More InfoCytokeratin 1 (Suprabasal Keratinocyte Marker) Antibody from MYBIOSOURCE INC.
Product Specific References1. Machesney et al. 1998. Am J Pathol. 152(5):1133-41. 2. Waseem et al. 1999. J Invest Dermatol. 112(3):362-9. 2. Leigh et al. 1993. Br J Dermatol. 129(2):110-9. 3. Bloor et al. 2003. Am J Pathol. 162(3):963-75.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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