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Antigenic Specificity | Cytokeratin 1 (Suprabasal Keratinocyte Marker) |
Clone | [LHK1] |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG2a, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Paraffin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10). Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis. |
Immunogen | Immunogen: A 13-amino acid peptide (VRFVSTSYSGVTR) from the C-terminus of human KRT1 protein |
Other Names | [67kDa Cytokeratin; CK1; Cytokeratin-1; EHK1; Epidermolytic hyperkeratosis 1; EPPK; K1; Keratin Type II Cytoskeletal 1; Keratin-1; KRT1; KRT1A; NEPPK; Type II cytoskeletal 1; Type-II keratin Kb1] |
Gene, Accession # | [KRT1], Gene ID: 3848, NCBI: NP_006112.3, UniProt: P04264 |
Catalog # | MBS4381043 |
Price | $190, $340, $340 |
Order / More Info | Cytokeratin 1 (Suprabasal Keratinocyte Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Machesney et al. 1998. Am J Pathol. 152(5):1133-41. 2. Waseem et al. 1999. J Invest Dermatol. 112(3):362-9. 2. Leigh et al. 1993. Br J Dermatol. 129(2):110-9. 3. Bloor et al. 2003. Am J Pathol. 162(3):963-75. |