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Antigenic Specificity | SMURF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti SMURF1 antibody recognizes E3 ubiquitin-protein ligase SMURF1, also known as hSMURF1, HECT-type E3 ubiquitin transferase SMURF1 and SMAD ubiquitination regulatory factor 1. It belongs to the HECT family of E3 ubiquitin ligases and controls osteoblast activity and bone homeostasis (Yamashita et al. 2005). It is involved in BMP receptor trafficking and signaling (Murakami and Etlinger 2018). SMURF1 plays a role in breast cancer migration and invasion by downregulating RhoA (Kwon et al. 2013). It also regulates cell migration by ubiquitinating tumor necrosis factor receptor-associated factor 4 (TRAF4) (Wang et al. 2013). |
Immunogen | Immunogen: A synthetic peptide corresponding to amino acids 66-96 of human SMURF1 |
Other Names | [SMURF1], [SMURF1; SMURF1; KIAA1625; hSMURF1] |
Gene, Accession # | [SMURF1], Gene ID: 57154, NCBI: NP_001186776.1, UniProt: Q9HCE7 |
Catalog # | MBS225603 |
Price | $375 |
Order / More Info | SMURF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |