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Antigenic Specificity | Phospho-BRAF-S445 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding S445 of human BRAF |
Other Names | [serine/threonine-protein kinase B-raf isoform 1; Serine/threonine-protein kinase B-raf; serine/threonine-protein kinase B-raf; B-Raf proto-oncogene, serine/threonine kinase; Proto-oncogene B-Raf; p94; v-Raf murine sarcoma viral oncogene homolog B1] |
Gene, Accession # | [BRAF], Gene ID: 673, NCBI: NP_004324.2, UniProt: P15056 |
Catalog # | MBS8574400 |
Price | $280 |
Order / More Info | Phospho-BRAF-S445 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |