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Antigenic Specificity | EPN1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: EPN1 antibody detects endogenous levels of EPN1. Description: EPN1 is an endocytic accessory protein that interacts with EPS15 (MIM 600051), the alpha subunit of the clathrin adaptor AP2 (AP2A1; MIM 601026), and clathrin (see MIM 118960), as well as with other accessory proteins for the endocytosis of clathrin-coated vesicles.[supplied by OMIM]Function: Binds to membranes enriched in phosphatidylinositol 4, 5-bisphosphate (PtdIns(4, 5)P2). Modifies membrane curvature and facilitates the formation of clathrin-coated invaginations (By similarity). Regulates receptor-mediated endocytosis.Subunit Structure: Monomer. Binds clathrin, ZBTB16/ZNF145 and ITSN1 (By similarity). Binds ubiquitinated proteins (By similarity). Binds |
Immunogen | Immunogen: A synthesized peptide derived from human EPN1 Subcellular Location: Cytoplasm. Cell Membrane. Nucleus. Membrane > Clathrin-Coated Pit. Associated with the cytoplasmic membrane at sites where clathrin-coated pits are forming. Colocalizes with clathrin and AP-2 in a punctate pattern on the plasma membrane. Detected in presynaptic nerve terminals and in Golgi stacks. May shuttle to the nucleus when associated with ZBTB16/ZNF145. Predicted Cross Reactivity: P |
Other Names | [EH domain binding mitotic phosphoprotein; EH domain-binding mitotic phosphoprotein; EPN 1; Epn1; EPN1_HUMAN; EPS 15 interacting protein 1; EPS-15-interacting protein 1; Epsin 1; Epsin-1] |
Gene, Accession # | [EPN1], Gene ID: 29924, NCBI: NP_001123543.1, UniProt: Q9Y6I3 |
Catalog # | MBS9600519 |
Price | $240, $280 |
Order / More Info | EPN1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |