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Antigenic Specificity | UBASH3A |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. Exhibits negligigle protein tyrosine phosphatase activity at neutral pH. May act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. May inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain. |
Immunogen | Immunogen: Recombinant Human Ubiquitin-associated and SH3 domain-containing protein A protein (287-455AA) |
Other Names | [Ubiquitin-associated and SH3 domain-containing protein A; Cbl-interacting protein 4; CLIP4; Suppressor of T-cell receptor signaling 2; STS-2; T-cell ubiquitin ligand 1; TULA-1; UBASH3A; STS2] |
Gene, Accession # | [UBASH3A], Gene ID: 53347, NCBI: NP_001001895.1, UniProt: P57075 |
Catalog # | MBS7105153 |
Price | $160, $235 |
Order / More Info | UBASH3A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |