CD320 (C-term), 153-182 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | CD320 (C-term), 153-182 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CD320 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-182 amino acids from the C-terminal region of human CD320. The CD320 antigen gene encodes the transcobalamin receptor(TCBLR). Cellular uptake of cobalamin (vitamin B12) is mediated byreceptors expressed on the cell surface. Transcobalamin II (TCN2;MIM 613441), a plasma protein secreted by endothelial cells, bindsthe cobalamin absorbed in the distal ileum and carries 10 to 30% oftotal circulating cobalamin. CD320 encodes a transcobalaminreceptor that binds TCN2-cobalamin at the plasma membrane andinternalizes the complex by endocytosis (Quadros et al., 2009[PubMed 18779389]). |
| Immunogen | n/a |
| Other Names | [CD320 antigen; 8D6 antigen; FDC-signaling molecule 8D6; FDC-SM-8D6; Transcobalamin receptor; TCblR; CD320; CD320; 8D6A] |
| Gene, Accession # | [CD320], Gene ID: 51293, NCBI: NP_001159367.1, UniProt: Q9NPF0 |
| Catalog # | MBS9213625 |
| Price | $165, $370 |
| Order / More Info | CD320 (C-term), 153-182 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Jiang, W., et al. Gene 466 (1-2), 49-55 (2010) : Pangilinan, F., et al. J. Med. Genet. 47(10):677-685(2010) Quadros, E.V., et al. Hum. Mutat. 31(8):924-929(2010) Quadros, E.V., et al. Blood 113(1):186-192(2009) Cho, W., et al. BMB Rep 41(12):863-867(2008) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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