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Antigenic Specificity | HLA class II histocompatibility antigen, DQ alpha 2 chain |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | caprylic acid ammonium sulfate precipitate |
Size | 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total HLA class II histocompatibility antigen, DQ alpha 2 chain polyclonal antibody. Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is |
Immunogen | Immunogen: Recombinant Human HLA class II histocompatibility antigen, DQ alpha 2 chain protein |
Other Names | [DX alpha chain; HLA class II histocompatibility antigen; DQ(6) alpha chain; HLA-DQA1; MHC class II DQA2; HLA-DQA2; HLA-DXA] |
Gene, Accession # | Gene ID: 3118, NCBI: NP_064440.1, UniProt: P01906 |
Catalog # | MBS9415181 |
Price | $320 |
Order / More Info | HLA class II histocompatibility antigen, DQ alpha 2 chain Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |