HLA class II histocompatibility antigen, DQ alpha 2 chain Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHLA class II histocompatibility antigen, DQ alpha 2 chain
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatcaprylic acid ammonium sulfate precipitate
Size0.1 mL
Concentration1.0 mg/ml
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous level of total HLA class II histocompatibility antigen, DQ alpha 2 chain polyclonal antibody. Binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. The peptide binding cleft accommodates peptides of 10-30 residues. The peptides presented by MHC class II molecules are generated mostly by degradation of proteins that access the endocytic route, where they are processed by lysosomal proteases and other hydrolases. Exogenous antigens that have been endocytosed by the APC are thus readily available for presentation via MHC II molecules, and for this reason this antigen presentation pathway is
ImmunogenImmunogen: Recombinant Human HLA class II histocompatibility antigen, DQ alpha 2 chain protein
Other Names[DX alpha chain; HLA class II histocompatibility antigen; DQ(6) alpha chain; HLA-DQA1; MHC class II DQA2; HLA-DQA2; HLA-DXA]
Gene, Accession #Gene ID: 3118, NCBI: NP_064440.1, UniProt: P01906
Catalog #MBS9415181
Price$320
Order / More InfoHLA class II histocompatibility antigen, DQ alpha 2 chain Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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