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Antigenic Specificity | SPART - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor. Multiple alternatively spliced variants, encoding the same protein, have been identified. Mutations associated with this gene cause autosomal recessive spastic paraplegia 20 (Troyer syndrome). |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SPG20 |
Other Names | [spartin; Spartin; spartin; spartin; Spastic paraplegia 20 protein; Trans-activated by hepatitis C virus core protein 1] |
Gene, Accession # | [SPART], Gene ID: 23111, NCBI: NP_001135766.1, UniProt: Q8N0X7 |
Catalog # | MBS3222528 |
Price | $335 |
Order / More Info | SPART - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |