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Antigenic Specificity | Mouse TCRgd |
Clone | [UC7-13D5] |
Host Species | Armenian Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | unconjugated |
Size | 0.5 mg |
Concentration | n/a |
Applications | Flow Cytometry; Immunohistochemistry (Frozen Sections); Immunoprecipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: gamma delta T-cell receptor (TCR) complex. The TCR gamma delta heterodimer of the CD3/T-cell receptor complex is clonotypic and consists of Ig-like variable and constant domains.1 It is expressed during thymopoiesis and on the small subpopulation of gamma delta TCRexpressing T lymphocytes in the periphery. The majority of T cells present in some epithelial tissues are gamma delta + and have limited receptor diversity.1, 2 The TCR gamma delta heterodimer recognizes peptide antigen bound to MHC antigens, and subsequent signal transduction mediated by the invariant chains leads to T cell activation.3 The monoclonal antibody UC7-13D5 is specific for the gamma delta heterodimer and plate-bound UC7-13D5 activates gamma delta TCR-bear |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS673497 |
Price | $260 |
Order / More Info | Mouse TCRgd Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Davis, M.M. 1990. Annu. Rev. Biochem. 59:475.2. Allison, J.P., and W.L. Havran. 1991. Annu. Rev. Immunol. 9:679.3. Klausner, R.D., and L.E. Samuelson. 1991. Cell 64:875.4. Dent, A.L., et al. 1990. Nature 343:714.5. Bluestone, J.A., et al. 1991. Immunol. Rev. 120:5.6. Houlden, B.A., et al. 1989. Cold Spring Harbor Symp. Quant. Biol. 54:45.7. Barrett, T.A., et al. 1991. Immunol. Res. 10:341.8. Unpublished observations. |