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Antigenic Specificity | CARD11 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL1 |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CARD11 |
Other Names | [caspase recruitment domain-containing protein 11; caspase recruitment domain-containing protein 11; caspase recruitment domain family member 11] |
Gene, Accession # | [CARD11], Gene ID: 84433, NCBI: NP_115791.3, UniProt: Q8TES3 |
Catalog # | MBS3220789 |
Price | $335 |
Order / More Info | CARD11 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |