SETDB1 (C-term), 1193-1225 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SETDB1 (C-term), 1193-1225 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse, Xenopus, zebrafish) |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This SETDB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1193-1225 amino acids from the C-terminal region of human SETDB1. The SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su(var)3-9 and 'Enhancer of zeste' proteins, from which the acronym SET is derived. Studies have suggested that the SET domain may be a signature of proteins that modulate transcriptionally active or repressed chromatin states through chromatin remodeling activities. |
| Immunogen | n/a |
| Other Names | [Histone-lysine N-methyltransferase SETDB1; ERG-associated protein with SET domain; ESET; Histone H3-K9 methyltransferase 4; H3-K9-HMTase 4; Lysine N-methyltransferase 1E; SET domain bifurcated 1; SETDB1; KIAA0067; KMT1E] |
| Gene, Accession # | [SETDB1], Gene ID: 9869, NCBI: NP_001138887.1, UniProt: Q15047 |
| Catalog # | MBS9210810 |
| Price | $165, $370 |
| Order / More Info | SETDB1 (C-term), 1193-1225 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Ichimura, T., et al., J. Biol. Chem. 280(14):13928-13935 (2005). Sarraf, S.A., et al., Mol. Cell 15(4):595-605 (2004). Wang, H., et al., Mol. Cell 12(2):475-487 (2003). Schultz, D.C., et al., Genes Dev. 16(8):919-932 (2002). Yang, L., et al., Biochem. J. 369 (PT 3), 651-657 (2003) (): (). |
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MYBIOSOURCE INC.
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