TDP1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TDP1 |
| Clone | [AT1F2] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b, k |
| Format | Protein G purified |
| Size | 0.05 mL, 0.1 mL |
| Concentration | 1mg/ml |
| Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Tyrosyl-DNA phosphodiesterase (TDP1) is a DNA repair enzyme that catalyzes the hydrolysis of a phophodiester bond between a tyrosine residue and a DNA 3' phosphate. This protein is a member of the phospholipase D (PLD) superfamily and contains two PLD phosphodiesterase domains. Mutations in TDP1 are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1) by interfering with DNA transcription or by inducting apoptosis in postmitotic neurons. |
| Immunogen | Immunogen: Recombinant human TDP1 (1-298aa) purified from E. coli |
| Other Names | [tyrosyl-DNA phosphodiesterase 1; FLJ11090; SCAN1], [TDP1; TDP1; Tyr-DNA phosphodiesterase 1] |
| Gene, Accession # | [TDP1], Gene ID: 55775, NCBI: NP_060789, UniProt: Q9NUW8 |
| Catalog # | MBS200157 |
| Price | $240, $315 |
| Order / More Info | TDP1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Dexheimer TS, et al., (2008) Anticancer Agents Med Chem. 8 (4):381-9; EI-Khamisy SF, Caldecott KW., (2006) Mutagenesis. 21 (4):219-24 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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