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Antigenic Specificity | PAK6 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human PAK6 (NP 064553.1). |
Other Names | [PAK5] |
Gene, Accession # | [PAK6], Gene ID: 56924, NCBI: Q9NQU5.1, UniProt: Q9NQU5 |
Catalog # | MBS8547065 |
Price | $280 |
Order / More Info | PAK6 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |