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Antigenic Specificity | SLFN5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.6mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total SLFN5 protein. Slfn5 (schlafen family member 5) is an 891 amino acid protein that exists as multiple alternatively spliced isoforms and is thought to play a role in hematopoeitic cell differentiation. The gene encoding Slfn5 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1, 200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involve |
Immunogen | Immunogen: Fusion protein of human SLFN5 Immunogen Type: Protein |
Other Names | [Homo sapiens schlafen family member 5, mRNA; Schlafen family member 5; schlafen family member 5; schlafen family member 5] |
Gene, Accession # | [SLFN5], Gene ID: 162394, NCBI: BC021238, UniProt: Q08AF3 |
Catalog # | MBS9430160 |
Price | $255 |
Order / More Info | SLFN5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |