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Antigenic Specificity | ICOSLG (C-term), 217-246 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ICOSLG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-246 amino acids from the C-terminal region of human ICOSLG. Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity). |
Immunogen | n/a |
Other Names | [ICOS ligand; B7 homolog 2; B7-H2; B7-like protein Gl50; B7-related protein 1; B7RP-1; CD275; ICOSLG; B7H2; B7RP1; ICOSL; KIAA0653] |
Gene, Accession # | [ICOSLG], Gene ID: 23308, NCBI: NP_056074.1, UniProt: O75144 |
Catalog # | MBS9203620 |
Price | $165, $370 |
Order / More Info | ICOSLG (C-term), 217-246 Antibody from MYBIOSOURCE INC. |
Product Specific References | Shimada, M., et al. Hum. Genet. 128(4):433-441(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Wang, K., et al. Hum. Mol. Genet. 19(10):2059-2067(2010) Pan, F., et al. Immunogenetics 62(4):237-251(2010) Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010) |