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Antigenic Specificity | NRBF2 - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro).Involved in starvation-induced autophagy probably by its association with PI3K complex I (PI3KC3-C1). However, effects has been described variably. Involved in the induction of starvation-induced autophagy. Stabilzes PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3. Proposed to negatively regulate basal and starvation-induced autophagy and to inhibit PIK3C3 activity by modulating interactions in PI3KC3-C1. May be involved in autophagosome biogenesis. May play a role in neural progenitor cell survival during differentiation. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NRBF2 |
Other Names | [nuclear receptor-binding factor 2 isoform 1; Nuclear receptor-binding factor 2; nuclear receptor-binding factor 2; nuclear receptor binding factor 2; Comodulator of PPAR and RXR] |
Gene, Accession # | [NRBF2], Gene ID: 29982, NCBI: NP_110386.2, UniProt: Q96F24 |
Catalog # | MBS3222078 |
Price | $335 |
Order / More Info | NRBF2 - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |