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Antigenic Specificity | STAT1 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human, monkey |
Isotype | IgG1 |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Mouse IgG monoclonal antibody for STAT1 detection. Tested with WB, IHC-P, ICC/IF, FCM in Human; Monkey.Background: Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene. The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This |
Immunogen | Immunogen: E Coli-derived human STAT1 recombinant protein (Position: S2-A230). Human STAT1 shares 91.2% amino acid (aa) sequence identity with mouse STAT1. Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3. Relevant Detection Systems: Relevant Detection Systems: We recommend Enhanced Chemiluminescent Kit with anti-Rabbit IgG (MBS176460) for Western blot, and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (MBS176453) for IHC(P) and ICC. |
Other Names | [Signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription 1, 91kDa; Signal transducer and activator of transcription 1-alpha/beta; Transcription factor ISGF-3 components p91/p84; STAT1] |
Gene, Accession # | [STAT1], Gene ID: 6772, NCBI: NP_009330.1, UniProt: P42224 |
Catalog # | MBS1752782 |
Price | $315 |
Order / More Info | STAT1 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1.Deberry C, Mou S, Linnekin D (October 1997). Stat1 associates with c-kit and is activated in response to stem cell factor. Biochem. J. 327 (1): 73-80. 2.Ouchi T, Lee SW, Ouchi M, Aaronson SA, Horvath CM (May 2000). Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes.Proc. Natl. Acad. Sci. U.S.A. 97 (10): 5208-13. 3.Zhang JJ, Vinkemeier U, Gu W, Chakravarti D, Horvath CM, Darnell JE (Dec 1996). Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling. Proc. Natl. Acad. Sci. U.S.A. 93 (26): 15092-6. |