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Antigenic Specificity | Metabotropic Glutamate Receptor 5/1a |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 10 Miniblots |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Frozen |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of excitatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse (Bhattacharya et al., 2004; Francesconi et al., 2004; Wilson and Nicoll, 2001). Group I metabotropic glutamate receptors (consisting of mGluR1 and mGluR5) are G-protein-coupled neurotransmitter receptors that are localized in the perisynaptic region of the postsynaptic membrane. When activated, Group I mGluRs lead to stimulation of phospholipase and activation of Protein Kinase C. In contrast activation of Group II metabotropic receptors (mGluR2 and mGluR3) leads to inhibition of adenylate cycla |
Immunogen | Immunogen: Synthetic peptide derived from the C-terminal region of the mGluR5 and mGluR1a proteins. |
Other Names | [metabotropic glutamate receptor 5; Metabotropic glutamate receptor 5; metabotropic glutamate receptor 5; metabotropic glutamate receptor 5b; metabotropic glutamate receptor (mGluR5); glutamate receptor, metabotropic 5], [Grm5; Grm5; mGluR5; mGlur5; Gprc1e; Mglur5; mGluR5] |
Gene, Accession # | Gene ID: 24418, NCBI: NP_058708.1, UniProt: P31424 |
Catalog # | MBS395851 |
Price | $440 |
Order / More Info | Metabotropic Glutamate Receptor 5/1a Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |