PI3KC3 (S34), 14-39 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-PI3KC3 (S34), 14-39 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | PI3KC3 (S34), 14-39 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: mouse, rat, porcine, Xenopus) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Immunofluorescence (IF), ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PI3KC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-39 amino acids from human PI3KC3. PI3KC3 is a catalytic subunit of the PI3K complex involved in the transport of lysosomal enzyme precursors to lysosomes. This enzyme acts catalytically to convert 1-phosphatidyl-1D-myo-inositol to 1-phosphatidyl-1D-myo-inositol 3-phosphate.Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targ |
| Immunogen | n/a |
| Other Names | [Phosphatidylinositol 3-kinase catalytic subunit type 3; PI3-kinase type 3; PI3K type 3; PtdIns-3-kinase type 3; Phosphatidylinositol 3-kinase p100 subunit; Phosphoinositide-3-kinase class 3; hVps34; PIK3C3; VPS34] |
| Gene, Accession # | [PIK3C3], Gene ID: 5289, NCBI: NP_002638.2, UniProt: Q8NEB9 |
| Catalog # | MBS9204783 |
| Price | $165, $370 |
| Order / More Info | PI3KC3 (S34), 14-39 Antibody from MYBIOSOURCE INC. |
| Product Specific References | References for protein: 1.Vergne, I., et al., J. Exp. Med. 198(4):653-659 (2003). 2.Volinia, S., et al., EMBO J. 14(14):3339-3348 (1995). References for U251 cell line: 1. Westermark B.; Ponten J.; Hugosson R. (1973). Determinants for the establishment of permanent tissue culture lines from human gliomas. Acta Pathol Microbiol Scand A. 81:791-805. [PMID: 4359449]. 2. Ponten, J.,Westermark B. (1978). Properties of Human Malignant Glioma Cells in Vitro. Medical Biology 56: 184-193.[PMID: 359950]. 3. Geng Y.;Kohli L.; Klocke B.J.; Roth K.A.(2010). Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent. Neuro Oncol. 12(5): 473-481.[ PMID: 20406898]. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies