SYT1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySYT1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
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DescriptionSpecificity: SYT1 antibody detects endogenous levels of total SYT1. Description: Synaptotagmin 1 (SYT1) is an integral membrane protein found in synaptic vesicles thought to play a role in vesicle trafficking and exocytosis (1). Individual SYT1 proteins are composed of an amino-terminal transmembrane region, a central linker region and a pair of carboxy-terminal C2 domains responsible for binding Ca2+ (2). The C2 domains appear to be functionally distinct, with the C2A domain responsible for regulating synaptic vesicle fusion in a calcium-dependent manner during exocytosis while the C2B domain allows for interaction between adjacent SYT1 proteins (3). Because synaptotagmin 1 binds calcium and is found in synaptic vesicles, this integral mem
ImmunogenImmunogen: A synthesized peptide derived from human SYT1 Subcellular Location: Cytoplasmic Vesicle > Secretory Vesicle > Synaptic Vesicle Membrane. Cytoplasmic Vesicle > Secretory Vesicle > Chromaffin Granule Membrane. Cytoplasm. Synaptic vesicles and chromaffin granules. Tissue Specificity: Expressed in melanocytes (PubMed:23999003).
Other Names[DKFZp781D2042; FLJ42519; p65; SVP65; Synaptotagmin 2; Synaptotagmin I; Synaptotagmin II; Synaptotagmin-1; SYT; Syt1; SYT1_HUMAN; Syt2; SytI]
Gene, Accession #[SYT1], Gene ID: 6857, NCBI: NP_001129277.1, UniProt: P21579
Catalog #MBS9606834
Price$240, $280
Order / More InfoSYT1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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