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Antigenic Specificity | KAT1 (HAT1) (C-term), 389-419 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse, rat) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This KAT1 (HAT1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 389-419 amino acids from the C-terminal region of human KAT1 (HAT1). Histone acetylation, particularly of histone H4, has been proposed to play an important role in replication-dependent nucleosome assembly. The HAT1 protein contains D, A, and B motifs, which are present in many N-acetyltransferases, including those that acetylate substrates other than histones. The HAT1 holoenzyme consists of 2 subunits: the catalytic 46-kD HAT1 and the accessory p46. The p46 subunit stimulated the activity of HAT1 and bound to core histones. The HAT1 holoenzyme acetylated newly synthesized but not nucleosomal histone H4 at lys5 and lys12, and, to |
Immunogen | n/a |
Other Names | [Histone acetyltransferase type B catalytic subunit; Histone acetyltransferase 1; HAT1; KAT1] |
Gene, Accession # | [HAT1], Gene ID: 8520, NCBI: NP_003633.1, UniProt: O14929 |
Catalog # | MBS9205636 |
Price | $165, $370 |
Order / More Info | KAT1 (HAT1) (C-term), 389-419 Antibody from MYBIOSOURCE INC. |
Product Specific References | Gronroos, E., et al., Mol. Cell 10(3):483-493 (2002). Makowski, A.M., et al., J. Biol. Chem. 276(47):43499-43502 (2001). Cheung, P., et al., Mol. Cell 5(6):905-915 (2000). Verreault, A., et al., Curr. Biol. 8(2):96-108 (1998). |