Edit |   |
---|---|
Antigenic Specificity | MyD88 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: MyD88 Polyclonal Antibody detects endogenous levels of MyD88 protein. MyD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. Myeloid differentiation primary response protein MyD88 functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human MyD88 |
Other Names | [Rabbit MyD88; MYD88; Myeloid differentiation primary response protein MyD88] |
Gene, Accession # | [MyD88], Gene ID: 4615, NCBI: NP_001166037.1, UniProt: Q99836 |
Catalog # | MBS9700695 |
Price | $250, $250 |
Order / More Info | MyD88 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |