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Antigenic Specificity | GFAP |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot, Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes human, mouse and rat GFAP. It cross-reacts with GFAPR416W and other GFAP mutant proteins. Glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. Phosphorylation of GFAP, and its association with annexin II-p2 and S-100, regulates GFAP polymerization. One of the first events that occurs during astrocyte proliferation is increased GFAP expression. Antibodies to GFAP have been detected in individuals with dementia, although the significance of this has not been conclusively determined. |
Immunogen | Immunogen: Synthetic peptide corresponding to aa 411-422 (KTVEMRDGEVIK) of human GFAP. This sequence is 100% identical to rat and mouse. |
Other Names | [glial fibrillary acidic protein isoform 2; Glial fibrillary acidic protein; glial fibrillary acidic protein; glial fibrillary acidic protein], [GFAP; GFAP; ALXDRD; GFAP] |
Gene, Accession # | [GFAP], Gene ID: 2670, NCBI: NP_001124491.1, UniProt: P14136 |
Catalog # | MBS191350 |
Price | $410 |
Order / More Info | GFAP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |