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Antigenic Specificity | GRM8 (C-term), 855-884 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.4 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This GRM8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 855-884 amino acids from the C-terminal region of human GRM8. L-glutamate is the major excitatory neurotransmitter inthe central nervous system and activates both ionotropic andmetabotropic glutamate receptors. Glutamatergic neurotransmissionis involved in most aspects of normal brain function and can beperturbed in many neuropathologic conditions. The metabotropicglutamate receptors are a family of G protein-coupled receptors,that have been divided into 3 groups on the basis of sequencehomology, putative signal transduction mechanisms, andpharmacologic properties. Group I includes GRM1 and GRM5 and these |
Immunogen | n/a |
Other Names | [Metabotropic glutamate receptor 8; mGluR8; GRM8; GPRC1H; MGLUR8] |
Gene, Accession # | [GRM8], Gene ID: 2918, NCBI: NP_000836.2, UniProt: O00222 |
Catalog # | MBS9200739 |
Price | $165, $370 |
Order / More Info | GRM8 (C-term), 855-884 Antibody from MYBIOSOURCE INC. |
Product Specific References | Saus, E., et al. J Psychiatr Res 44(14):971-978(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Fonseca, F., et al. Mol Diagn Ther 14(3):171-178(2010) Bozaoglu, K., et al. J. Clin. Endocrinol. Metab. 95(5):2476-2485(2010) Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010) |