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Antigenic Specificity | PDGF Receptor alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.79 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total PDGF Receptor alpha protein. This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. [provid |
Immunogen | Immunogen Type: Recombinant Protein Immunogen Description: Recombinant fragment contain a sequence corresponding to a region within amino acids 331 and 709 of PDGF Receptor alpha. |
Other Names | [CD140A; MGC74795; PDGFR2; RHEPDGFRA; PDGFRA; CD140 antigen-like family member A; CD140a antigen; PDGF-R-alpha; rearranged-in-hypereosinophilia-platelet derived growth factor receptor] |
Gene, Accession # | [PDGF], Gene ID: 5156, NCBI: NP_006197.1, UniProt: P16234 |
Catalog # | MBS9406032 |
Price | $320 |
Order / More Info | PDGF Receptor alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |