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Antigenic Specificity | NR2B Glutamate Receptor, 20-271 |
Clone | [S59-36] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunoblot; Immunohistochemistry; Immunocytochemistry; Immunofluorescence |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: NR2B Glutamate Receptor. This antibody recognizes human, mouse, and rat NR2B. It does not cross-react with NR2A. Glutamate receptors of the NMDA subtype are involved in several physiological and pathological processes in the brain. Functional NMDA receptors are heteromultimeric complexes of the NR1 subunit and one or more of the four NR2 subunits (NR2A-D). Coexpression of both subunit types are required for the formation of fully functional channels that are inserted into the plasma membrane. The NR2 subunit determines characteristics of the channel such as conductance, mean open time, and sensitivity to Mg+2. The ability of NR1 and NR2 subunit combinations to flux Ca+2 is essential to the role that NMDA receptors play in synap |
Immunogen | Antigen: Fusion protein aa 20-271 (extracellular N-terminus) of rat NR2B (accession no. Q00960). This sequence is 99% identical to human and mouse. |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | MBS190518 |
Price | $410 |
Order / More Info | NR2B Glutamate Receptor, 20-271 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |