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Antigenic Specificity | DUSP3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse, rat. |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene maps in a region that contains the BRCA1 locus which confers susceptib |
Immunogen | Immunogen: Rabbit polyclonal DUSP3 (1) antibody was raised against a recombinate human DUSP3 protein 2-144aa (BC035701). |
Other Names | [DUSP3 protein; Dual specificity protein phosphatase 3; dual specificity protein phosphatase 3; dual specificity protein phosphatase VHR; serine/threonine specific protein phosphatase; vaccinia H1-related phosphatase; vaccinia virus phosphatase VH1-related; dual specificity phosphatase 3; Dual specificity protein phosphatase VHR; Vaccinia H1-related phosphatase; VHR], [DUSP3; DUSP3; VHR] |
Gene, Accession # | [DUSP3], Gene ID: 1845, NCBI: AAH35701.1 |
Catalog # | MBS416230 |
Price | $230 |
Order / More Info | DUSP3 Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Wang,J.Y., Yeh,C.L., Chou,H.C. et al. Vaccinia H1-related phosphatase is a phosphatase of ErbB receptors and is down-regulated in non-small cell lung cancer. J. Biol. Chem. 286 (12), 10177-10184 (2011). |