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Antigenic Specificity | TYK2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Tyk2, a member of the Jak family of protein tyrosine kinases, associates with and is activated by receptors for many cytokines including IL-13, the IL-6 family, IL-10, and interferon-alpha and beta (1-3). Following ligand binding, Tyk2 is activated by phosphorylation on Tyr1054 and/or Tyr1055 (4). Tyk2 is required for the tyrosine phosphorylation of Stat3 in the IFN-beta signaling cascade (5). |
Immunogen | Immunogen: Recombinant Protein |
Other Names | [JTK1], [TYK2; TYK2; JTK1; IMD35] |
Gene, Accession # | [TYK2], Gene ID: 7297, NCBI: P29597.3, UniProt: P29597 |
Catalog # | MBS126617 |
Price | $200, $275, $430 |
Order / More Info | TYK2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |