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Antigenic Specificity | HK1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human. predicted: mouse, rat. |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein. [provided by RefSeq, Apr 2009] |
Immunogen | Immunogen: Rabbit polyclonal HK1 (1) antibody was raised against a recombinate human HK1 protein 351-629aa (BC008730). |
Other Names | [hexokinase-1 isoform HKI; Hexokinase-1; hexokinase-1; HK I; brain form hexokinase; glycolytic enzyme; hexokinase type I; hexokinase 1; Brain form hexokinase; Hexokinase type I; HK I], [HK1; HK1; HKD; HKI; HXK1; HMSNR; HK1-ta; HK1-tb; HK1-tc] |
Gene, Accession # | [HK1], Gene ID: 3098, NCBI: NP_000179.2 |
Catalog # | MBS416527 |
Price | $230 |
Order / More Info | HK1 Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Gjesing,A.P., Nielsen,A.A., Brandslund,I. et al. Studies of a genetic variant in HK1 in relation to quantitative metabolic traits and to the prevalence of type 2 diabetes. BMC Med. Genet. 12, 99 (2011). |