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Antigenic Specificity | Human RUVBL1 |
Clone | [2943C1a] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 100 ug/ml (1.0 ml) |
Applications | Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem |
Immunogen | n/a |
Other Names | [Homo sapiens RuvB-like 1 (E. coli) (RUVBL1); RVB1; ECP54;TIP49; NMP238; TIP49A], [RUVBL1; RUVBL1; RVB1; TIH1; ECP54; TIP49; INO80H; NMP238; PONTIN; TIP49A; Pontin52] |
Gene, Accession # | [RUVBL1], Gene ID: 8607, NCBI: NP_003698.1 |
Catalog # | MBS120207 |
Price | $395 |
Order / More Info | Human RUVBL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |