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Antigenic Specificity | Phospho-SNCA-Y125 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. |
Immunogen | Immunogen: A phospho specific peptide corresponding to residues surrounding Y125 of human SNCA Calculated Molecular Weight: 18kDa |
Other Names | [Phospho-SNCA-Y125: PD1; NACP; PARK1; PARK4], [SNCA; SNCA; PD1; NACP; PARK1; PARK4; NACP; PARK1; NACP] |
Gene, Accession # | [SNCA], Gene ID: 6622, NCBI: P37840.1, UniProt: P37840 |
Catalog # | MBS128506 |
Price | $235, $350, $525 |
Order / More Info | Phospho-SNCA-Y125 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |