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Antigenic Specificity | EXOSC5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Non-catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDN |
Immunogen | Immunogen: Recombinant human Exosome complex component RRP46 protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-131154 |
Other Names | [Exosome complex component RRP46; EXOSC5; CML28; RRP46; Chronic myelogenous leukemia tumor antigen 28; Exosome component 5; Ribosomal RNA-processing protein 46; p12B], [EXOSC5; EXOSC5; p12B; RRP46; RRP41B; Rrp46p; hRrp46p; CML28; RRP46] |
Gene, Accession # | [EXOSC5], Gene ID: 56915, NCBI: NP_064543.3, UniProt: Q9NQT4 |
Catalog # | MBS1493623 |
Price | $160, $235 |
Order / More Info | EXOSC5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |