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Antigenic Specificity | NALP4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NALP4 Antibody: NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP4, also known as PYRIN-containing APAF1-like protein 4, has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. In transfected 293 cells, NALP4 suppressed NF-κB induction by TNF-α and IL-1β, suggesting NALP4 operates at a point of convergence in these two signaling pathways. NALP4 also suppressed NF-κB induction resulting from overexpression of several adapter proteins and protein kinases involved in these pathways, including TRAF |
Immunogen | Immunogen: NALP4 antibody was raised against a 13 amino acid synthetic peptide near the center of human NALP4. Buffer: NALP4 Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [NALP4; CT58; PAN2; RNH2; NALP4; PYPAF4; CLR19.5; NACHT; LRR and PYD domains-containing protein 4; PAAD and NACHT-containing protein 2; CT58; NLR family, pyrin domain containing 4], [NLRP4; NLRP4; CT58; PAN2; RNH2; NALP4; PYPAF4; CLR19.5; NALP4; PAN2; PYPAF4; RNH2; CT58; PAN2; PYPAF4] |
Gene, Accession # | [NLRP4], Gene ID: 147945, NCBI: AAL35293, UniProt: Q96MN2 |
Catalog # | MBS150202 |
Price | $375 |
Order / More Info | NALP4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |